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CAN YOU HELP RICK?
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TPI-Helpathon #5b
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From
10/13/2021
until
10/14/2021
13h00-13h00
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Volunteer wanted
Objective: Finding the best human models for researching the effect of the essential amino acid (leucine) on the muscle blood flow. 
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Rick Meijer is a clinician at the Amsterdam UMC and specialized in vascular medicine. He wants to develop a personalized preventative treatment for his diabetes patients.

Insulin ensures the absorption of sugar in the muscles. It also increases the blood circulation in the muscles, which has a positive effect on the absorption of sugar. Rick is investigating in mice and in humans whether leucine, an essential amino acid (found in a.o. nuts and dairy) has a negative effect on the blood circulation in muscles. If so, it may reduce the effectiveness of insulin and play a part in the development of type 2 diabetes mellitus. There are a lot of advantages to using mice in this research. Results obtained through human models are more relevant, but they are harder to carry out for all sorts of reasons - practical, ethical and legal.

“In my work I see many diabetes patients and the complications of this disease they face. I also see remarkable differences in the development of this disease. It would be great if this research on the effect of leucine can allow me and my colleagues to provide better and personalized care to my patients in the future. And I'm sure if we can solve this puzzle with human models, the solution can be applied in other areas as well.”

Rick wants to  find the best suitable human models for his research on the effect of leucine on muscle blood flow? Can you help him?


Register below to help science and Rick move forward! 

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